Migraine

This review is a pragmatic attempt to highlight recent research and background material in migraine. It should not be considered exhaustive, simply a way of reviewing some of the major developments and current thinking in the area.

Click here to see all the TRIP Evidence Reviews.

Evidence-Based Reports

• Propranolol for migraine prophylaxis Bandolier, 2007
• SSRI for migraine prophylaxis Bandolier, 2007
• Anticonvulsants for migraine prophylaxis Bandolier, 2007
• Naratriptan for acute migraine Bandolier, 2007
• Emergency care evidence in practice series - management of migraine National Institute of Clinical Studies (Australia), 2006

Recent Clinical Guidelines

• Migraine. PRODIGY, 2006
• Special treatment situations: pediatric migraine. Standards of care for headache diagnosis and treatment. National Headache Foundation, 2004
• Treatment of primary headache: preventive treatment of migraine. Standards of care for headache diagnosis and treatment. National Headache Foundation, 2004
• Guidelines for All Healthcare Professionals in the Diagnosis and Management of Migraine, Tension-Type, Cluster and Medication-Overuse Headache. British Association for the Study of Headache, 2007

Recent articles in core journals

• Early Intervention With Almotriptan: Results of the AEGIS Trial (AXERT((R)) Early Migraine Intervention Study). Headache, 2007
• Effectiveness and tolerability of acupuncture compared with metoprolol in migraine prophylaxis. Headache, 2006
• Cost-effectiveness of migraine prevention: the case of topiramate in the UK. Cephalalgia, 2006
• Treatment of childhood migraine attacks with oral zolmitriptan and ibuprofen. Neurology, 2006
• Diclofenac epolamine is effective in the treatment of acute migraine attacks. Cephalalgia, 2007
• Migraine and risk of cardiovascular disease in women. JAMA, 2006
• Medications for Migraine Prophylaxis. American Family Physician, 2006

eTextbooks

• eMedicine
• Ganfyd
• Merck Manual
• GP Notebook

Clinical Queries

• For a woman with heavy menses who has developed migraine with aura using oral contraception, which other contraceptive methods can be used safely? FFPRHC, 2007
• What is the risk of ischaemic stroke for women of various ages with migraine of various types? Is the risk modified by use of transdermal oestradiol patches to control menstrual migraine? FFPRHC, 2005
• Any evidence of beneficial effect of daily low dose aspirin (75mg daily) in prevention of migraine? ...or prevention of long term consequences of migraine? NLH, 2006
• Is hormone replacement therapy (HRT) contra-indicated in focal/classical migraine? ATTRACT, 2006

Patient information

• Stroke and migraine Better Health Channel
• Migraine NHS Direct
• Migraine Headache FAQs eMedicine Consumer Health
• Migraine Patient UK
• Headache, migraine Mayo Clinic